منابع مشابه
Adaptive mutation: has the unicorn landed?
Reversion of an episomal Lac- allele during lactose selection has been studied as a model for adaptive mutation. Although recent results show that the mutations that arise during selection are not "adaptive" in the original sense, the mutagenic mechanism that produces these mutations may nonetheless be of evolutionary significance. In addition, a transient mutational state induced in a subpopul...
متن کاملThe particle has landed--characterizing the fate of inhaled pharmaceuticals.
Although there is a modest body of literature on the absorption of inhaled pharmaceuticals by normal lungs and some limited information from diseased lungs, there is still a surprising lack of mechanistic knowledge about the details of the processes involved. Where are molecules absorbed, what mechanisms are involved, how well are different lung regions penetrated, what are the determinants of ...
متن کاملHouston, GEMINI has landed: Spinal cord fusion achieved
One of the keys to a successful spinal cord fusion is a very sharp cut that minimizes damage of the cord, both at the white matter and the gray matter level. This allows the two interfaces of a severed cord to regrow neurites out of the gray matter core, the vital component of the sensorimotor machinery that makes us move and feel (the so‐called cortico‐trunco‐reticulo‐proprio‐spinal pathway, C...
متن کاملUltra-LAMA, ultra-LABA, ultra-inhaled steroids? The future has landed.
We humans tend to believe that the world has always existed in the form in which we know it. History is fine as an object of study, but we rarely make the effort to really situate ourselves in the past. If we ask most pulmonologists who have started or finished their training this century about the origins of inhaled treatment for obstructive lung disease, we might be surprised to find how litt...
متن کاملThe SeaLion has Landed: An IDE for Answer-Set Programming - Preliminary Report
We report about the current state and designated features of the tool SeaLion, aimed to serve as an integrated development environment (IDE) for answer-set programming (ASP). A main goal of SeaLion is to provide a userfriendly environment for supporting a developer to write, evaluate, debug, and test answer-set programs. To this end, new support techniques have to be developed that suit the req...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Science
سال: 2017
ISSN: 0036-8075,1095-9203
DOI: 10.1126/science.aaq0143